Clinical trial doctor in hospital using Aces Health

The Real Cost of Nonadherence

Jordan Innovation

Clinical trials are the cutting edge of today’s biomedical innovation, powering new scientific achievements and advances in what we know about human illness. But to many patients, clinical trials also represent something much more personal: the best hope for a normal, healthier life.

This is why pharmaceutical and biotech sponsors devote $60+ billion to clinical trials annually. When there’s so much at stake in healthcare research, continually getting it right is the most critical part of the process. But for some reason it doesn’t always happen that way: almost one-third of funded trials never successfully finish, including research for society’s most harmful diseases like cancer, diabetes, and HIV. What causes this gap in expectation and reality? And how can we ensure that more of these life-changing and life-saving medicines make it through the investigation process?

When we crunch the numbers, we can see that all too often the failure of these drugs to make it to market actually has nothing to do with their medical effectiveness. Rather, the blame lies with the problems in today’s standard clinical research processes, and one huge driving factor is poor patient adherence to study protocols. With rates in many trials ranging anywhere from 43% to 78%, the detrimental effects of nonadherence are causing tangible issues for researchers… and they’re getting worse. In 2001 approximately 50% of clinical trial participants made it from screening to successful completion of the trial. By 2010, that percentage had dropped to just 25%.

What if we could make life easier on the patients in clinical trials, and researchers could leverage mobile technology and intuitive design to make adherence to study protocols quick, simple, and maybe even fun?

At Aces Health, that’s the challenge we set out to solve. The Aces platform integrates the latest in mobile and Bluetooth technology to ensure doses aren’t missed and to enable one touch (and even no touch) data reporting. Aces’ streamlined communication features allows investigators to stay on top of individual and study-wide adherence in real time, heading off potential issues before data is compromised.  When a 20% decrease in adherence means expanding sample sizes by 50% or more, Aces could save study sponsors millions.

Aces is more than just clinical trials. We know that medication adherence is a huge issue for healthcare providers, patients, and caretakers globally. Deviations in medical adherence lead to 125,000 deaths per year, $290 billion in annual costs, and account for 69% of all medical-related hospital admittance. Even just in the United States, every 1% increase in medication adherence can cause Medicare spending to fall .2%…that’s about $1 billion in savings for U.S. taxpayers!

So talk to us about how we can help your clinical trials run more effectively. Together we can power better medicine, and better health, for everyone.